Now recruiting in Perth

Are you peri- or post-menopausal?

Help researchers investigate whether curcumin supplementation can support cognitive performance and wellbeing during the menopausal transition.

Generally healthy women aged 40–65 who are peri- or early postmenopausal and have concerns about memory, concentration, attention, word-finding or clear thinking may be eligible.

Check if you’re eligible Read the information sheet

Online questionnaire · Confidential · No obligation

About the research

An independently managed clinical trial

Research suggests curcumin, a compound derived from turmeric, may support cognitive performance, mood and general wellbeing in adults. Limited research has examined these outcomes in women during the menopausal transition.

This randomised, double-blind, placebo-controlled study will examine cognitive performance, mood, sleep, pain and other menopause-related symptoms. Blood markers associated with inflammation, glucose regulation and appetite-regulating hormones will also be measured.

The study is funded by Dolcas Biotech LLC, the producer of Curcugen®, and is independently conducted and managed by Clinical Research Australia in accordance with the approved protocol and applicable ethical and scientific standards.

What participation involves

Your participation at a glance

Check if you’re eligible →

Apply online

Complete a confidential eligibility questionnaire (about 10 minutes).

Telephone interview

A researcher will discuss the study, answer questions and assess your eligibility (about 15 minutes).

Attend visit 1

Visit our Duncraig clinic for health measurements, a blood sample, questionnaires and cognitive testing (about 60–90 minutes).

Take study capsules

Take one curcumin or placebo capsule twice daily with food for 12 weeks.

Complete online questionnaires

Complete brief online questionnaires at weeks 4 and 8 (about 10 minutes each).

Attend visit 2

Return at week 12 for follow-up measurements, a blood sample, questionnaires and cognitive testing (about 60 minutes).

Who may be suitable?

You may be eligible if:

You are a woman aged 40–65 years
You have an intact uterus and at least one ovary
You are perimenopausal or within six years of your final menstrual period
You have experienced cognitive difficulties during most weeks over the previous three months
Your cognitive difficulties began or became noticeably worse during the menopausal transition
Your BMI is between 18 and 35 kg/m²
You can attend two appointments in Duncraig

Time and travel

Participant compensation

Participants receive a $40 gift voucher at the first visit and a $120 gift voucher at the final visit. Participants allocated to placebo are also offered a complimentary 12-week supply of curcumin after completing the study.

Ethics approvedNIIM Ethics Committee · Ref. 0166E_2026

Registered trialAustralian & New Zealand
Clinical Trials Registry

Experienced team5,000+ participants
in past studies

ConfidentialVoluntary participation
and protected details

Take the first step

Could this study be right for you?

Complete the short, confidential questionnaire to help our research team assess your eligibility. Applying does not commit you to taking part.