Mood & wellbeing01
Saffron for adults experiencing low mood
- Design
- Randomised, double-blind, placebo-controlled trial
- Outcomes assessed
- Depressive symptoms, anxiety, stress, sleep and general wellbeing
Completed research
Selected clinical trials delivered by CRA.
A representative portfolio of peer-reviewed human research across natural-health ingredients, populations and outcomes.
Demonstrated capability
Rigorous studies. Meaningful questions. Transparent publication.
Our completed work demonstrates experience across study design, participant recruitment, trial delivery, data analysis and scientific publication.
The examples below are selected to show the breadth of CRA’s research capability. Publication links provide the full methods, findings, limitations and disclosures for each study.
Cognition & sleep02
Magnesium L-threonate for cognition and sleep
- Design
- Randomised, double-blind, placebo-controlled trial
- Outcomes assessed
- Objective cognition, working memory, reaction time, sleep and physiological measures
Adolescent cognition03
Lutein and zeaxanthin in healthy teenagers
- Design
- Randomised, double-blind, placebo-controlled trial
- Outcomes assessed
- Macular pigment, attention, processing speed, memory and visual reasoning
Women’s health04
Saffron for menopausal complaints
- Design
- Randomised, double-blind, placebo-controlled trial
- Outcomes assessed
- Mood, menopausal symptoms, sleep and quality of life
Stress & mental health05
Ashwagandha for adults experiencing high stress
- Design
- Randomised, double-blind, placebo-controlled trial
- Outcomes assessed
- Anxiety, stress, cortisol, DHEA-S and testosterone
Cognitive performance06
Lutein and zeaxanthin in adults with cognitive complaints
- Design
- Randomised, double-blind, placebo-controlled trial
- Outcomes assessed
- Visual memory, learning, cognitive performance, mood and physical function
Eye health & digital screens07
Lutein and zeaxanthin for regular screen users
- Design
- Randomised, double-blind, placebo-controlled trial
- Outcomes assessed
- Macular pigment, visual function, eye strain, sleep and psychological outcomes
Stress & fatigue08
Ashwagandha in adults with high stress and fatigue
- Design
- Randomised, double-blind, placebo-controlled trial
- Outcomes assessed
- Perceived stress, fatigue, mood, hormones, inflammation and heart-rate variability
Pain & joint health09
Topical curcumin for knee osteoarthritis pain
- Design
- Randomised, double-blind, placebo-controlled trial
- Outcomes assessed
- Knee pain, osteoarthritis symptoms, daily pain ratings, physical performance and rescue medication use
Women’s health10
Khaya senegalensis for menopausal symptoms
- Design
- Randomised, double-blind, placebo-controlled trial
- Outcomes assessed
- Menopausal symptoms, sleep, fatigue, vasomotor symptoms, digestive symptoms and tolerability
Mood, sleep & wellbeing11
Saffron for women experiencing low mood and poor sleep
- Design
- Randomised, double-blind, placebo-controlled trial
- Outcomes assessed
- Depressive symptoms, sleep, self-esteem, physical appearance and facial skin age
Stress & sleep12
Holy basil for adults experiencing stress
- Design
- Randomised, double-blind, placebo-controlled trial
- Outcomes assessed
- Perceived stress, mood, sleep, hair and salivary cortisol, and physiological responses to acute stress
Credible evidence
Research designed to support confident decisions.
Completed studies are presented as examples of CRA’s research capability. Our role is to generate robust, clearly interpreted evidence that supports product development and withstands scientific scrutiny.
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