DO YOU HAVE PROBLEMS WITH YOUR MEMORY OR ATTENTION?

Volunteers are needed to examine the effects of an Indian plant on memory, attention, and mood in adults

This is a registered clinical trial with the Australian and New Zealand Clinical Trials Registry (https://www.anzctr.org.au/ACTRN12623000225617.aspx)

About this study

This study is only available for people able to travel to our office in Duncraig, WA 6023

Bacopa monnieri (Brahmi), a plant native to India, is traditionally used in Ayurvedic medicine as a neural tonic, sedative, memory, and learning enhancer. In this study, we are interested in examining its effects on memory, attention, stress and energy in adults aged 40 to 70 with concerns about their memory.

PLEASE NOTE:  Travel to our office located in Duncraig is required at the beginning and end of the study

There is no cost for participating in this study. To compensate you for your time and travel costs, you will be given a $40 Coles/Myer group gift voucher each time you visit our office (on 2 occasions).

If you are between 40 and 70 years old and believe you have problems with your memory or attention, we invite you to participate in this randomised, controlled study.

What does participating in this study involve?

Eligible participants will be RANDOMLY allocated into ONE of TWO treatment conditions:

  1. Daily intake of capsules containing Bacopa monnieri, or
  2. Daily intake of placebo (fake) capsules

This 12-week study consists of the following:

  1. Participate in a 20-minute phone interview to discuss the study and assess your eligibility to participate. During this interview, we will also conduct a brief assessment of your memory and attention.
  2. Attend a face-to-face assessment on 2 occasions (baseline and week 12) located in our offices in Duncraig. During these 90-minute visits, we will collect a fasting blood sample from you, and we will measure your blood pressure, weight and height. You will also complete several computer-based tests assessing your attention/ memory and will need to complete several questionnaires.
  3. Take the capsules for 12 weeks (1 capsule twice daily, containing either placebo or Bacopa Monnieri)
  4. Complete online questionnaires every 2 weeks. This will take approximately 5 to 15 minutes.

Please Note: People on the placebo will be provided with a FREE 12-week supply of Bacopa capsules at the end of the study

You can download the full STUDY INFORMATION SHEET by clicking on the button at the bottom of this webpage.

Click on the image below to view the study design and requirements. 

What is the criteria for participating in this study?

To be INCLUDED in the study, the following inclusion criteria must be met:

  1. You are a generally healthy adult (male or female)
  2. You are aged between 40 to 70 years
  3. You reside in independent living accommodation
  4. You report experiencing problems with your memory or attention
  5. You are a non-smoker
  6. You have a body mass index (BMI) between 18 and 35 kg/m2
  7. You have no plan to commence any new treatments over the study period
  8. You are willing to provide a personally signed and dated informed consent form detailing all pertinent aspects of the trial.

If any of the exclusion criteria below is met, you will not be suitable for participation in this study:

  1. You suffer from a recently diagnosed or unmanaged medical condition including but not limited to: diabetes, hyper/hypotension, cardiovascular disease, gallbladder disease, autoimmune disease, endocrine disease, or cancer/ malignancy
  2. You have been diagnosed with a psychiatric disease (other than mild-to-moderate depression or anxiety) and/or neurological condition/ disease (e.g., Parkinson’s or Alzheimer’s disease)
  3. You have a history of paralysis, stroke, seizures, or head injury (with loss of consciousness).
  4. You regularly take medications including but not limited to anticholinergics, acetylcholinesterase inhibitors, or steroid medications
  5. You have changed your medication (dose or type) in the last 3 months, or you expect to change it during the study
  6. You currently take supplements containing Bacopa Monnieri or other herbal ingredients that might affect the study outcomes.
  7. In the last 6 months, you have commenced or changed your dose of nutritional and/or herbal supplements that may impact on treatment outcome
  8. You currently (or in the last 12 months) have a problem with the use of illicit drugs
  9. You drink more than 14 standard servings of alcohol per week
  10. You are pregnant, breastfeeding, or intend to fall pregnant in the next 3 months
  11. You fall pregnant during the study
  12. You have had a significant surgery in the last 12 months
  13. You do overnight shift work
  14. You plan on making major lifestyle change in the next 3 months

Has this study received ethics approval?

This study has been approved by the National Institute of Integrative Medicine (NIIM) Ethics Committee (Reference number: 0112E_2022)

How can I apply for this study?

If you are interested in participating in this study, click the button below to complete the initial screening questionnaire. This questionnaire will take 10 minutes to complete and will help us assess your eligibility to participate in this study.

Please Note: All answers are confidential and will only be seen by study investigators. If you are not eligible to participate in this study, your records will be deleted immediately

If you are interested in participating in this study, click on the button below to complete the initial screening questionnaire. This questionnaire will take 10 minutes to complete and helps us assess your eligibility for the study.

Please Note: All answers are confidential and will only be seen by study investigators. If you are not eligible to participate in this study, your records will be deleted immediately

Are you interested in participating in a study?

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Your privacy is assured. We will only contact you when we have new studies commencing and require volunteers.